2-(4-Aminophenyl)butanoic acid(CAS: 29644-97-1)

2-(4-Aminophenyl)butanoic acid is a white crystalline solid with a molecular weight of 221.23 g/mol. It is slightly soluble in water and ethanol. The compound exhibits basic properties due to its amine functionality and is reactive towards acidic conditions. It shows good solubility in organic solvents like methanol and acetone. This compound is stable under normal conditions but should be stored in a dry, cool place away from direct sunlight.

2-(4-Aminophenyl)butanoic acid is commonly synthesized via the condensation of 4-aminophenol with butanoic acid in the presence of a catalyst such as p-toluenesulfonic acid. The reaction is typically carried out in an organic solvent like methanol or ethanol. The yield of the product is around 70-80%, and the purity can be increased through recrystallization from hot ethanol.

2-(4-Aminophenyl)butanoic acid is utilized in various industries. In pharmaceuticals, it serves as a precursor for the synthesis of bioactive compounds. It is also used in the production of polymers, where its amine functionality allows for the formation of specific chemical bonds. Additionally, it has applications in sensors and semiconductors due to its reactive properties and ability to form stable complexes.

When handling 2-(4-Aminophenyl)butanoic acid, it is important to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. The compound should be stored in a well-ventilated area away from direct sunlight. It should be handled in a fume hood to minimize exposure to fumes. In case of a spill, the area should be flushed with water and the contaminated material disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed safety information.