4-Bromophenylalanine(CAS: 62561-74-4)

4-Bromophenylalanine, CAS 62561-74-4, is a white crystalline solid with a molecular weight of approximately 242.04 g/mol. It is slightly soluble in water and more soluble in organic solvents like ethanol and methanol. Chemically, it is less reactive compared to phenylalanine, making it suitable for various modifications and derivatizations. It has a melting point of around 245-247 °C and is stable under normal conditions but should be kept away from strong acids and bases.

4-Bromophenylalanine can be synthesized from phenylalanine via bromination reactions. Typically, phenylalanine is treated with bromine in the presence of a Lewis acid like aluminum bromide (AlBr3) or n-butyllithium (n-BuLi). The reaction involves the displacement of the amino group by bromine, yielding 4-bromophenylalanine. This method allows for high selectivity and good yield, making it a common approach in the laboratory and industry.

4-Bromophenylalanine, CAS 62561-74-4, is primarily used in the pharmaceutical industry for the synthesis of various drug candidates, particularly those requiring modifications of amino acid structures. It is also used in polymer science for the development of novel materials and in sensor technology for detection of specific compounds. Additionally, it has potential applications in semiconductor manufacturing for the production of advanced materials.

When handling 4-Bromophenylalanine, CAS 62561-74-4, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be stored in a cool, dry place away from direct sunlight and in a fume hood to avoid inhalation. In case of a spill, immediately clean up and dispose of the waste according to local regulations. It is advisable to refer to the Safety Data Sheet (SDS) for detailed handling and safety information.