Ethyl 5-(2-fluorophenyl)-1H-pyrrole-3-carboxylate(CAS: 881674-06-2)

Ethyl 5-(2-fluorophenyl)-1H-pyrrole-3-carboxylate (CAS: 881674-06-2) is a crystalline compound with a molecular weight of approximately 224.21 g/mol. It has a solubility in water of about 3 g/L. This compound exhibits good reactivity, particularly with nucleophiles, and is often used in organic synthesis. It is stable under normal conditions but should be stored in a cool, dry place away from strong oxidizing agents.

Ethyl 5-(2-fluorophenyl)-1H-pyrrole-3-carboxylate (CAS: 881674-06-2) is typically synthesized via a multistep process involving the formation of a pyrrole derivative and subsequent coupling with an ethyl ester. This reaction is often catalyzed by a palladium complex, and the overall yield can be up to 85%. The reaction conditions include the use of a base and a solvent such as toluene or dioxane.

Ethyl 5-(2-fluorophenyl)-1H-pyrrole-3-carboxylate (CAS: 881674-06-2) is primarily used in the pharmaceutical and chemical industries. It serves as a precursor in the synthesis of various bioactive compounds and is also utilized in the production of advanced materials such as polymers and organic semiconductors. Its fluorescent properties make it useful in sensor applications as well.

When handling Ethyl 5-(2-fluorophenyl)-1H-pyrrole-3-carboxylate (CAS: 881674-06-2), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be stored in a cool, well-ventilated area and handled in a fume hood to minimize exposure. In case of a spill, immediately clean it up with appropriate absorbent material and dispose of it according to local regulations. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.