4-(Diethoxymethyl)benzaldehyde(CAS: 81172-89-6)

4-(Diethoxymethyl)benzaldehyde is a crystalline solid with a molecular weight of approximately 216.26 g/mol. It is slightly soluble in water but soluble in organic solvents like ethanol and acetone. The compound is moderately reactive, particularly with nucleophiles, and can undergo substitution reactions. It has a melting point of around 58-59°C and a boiling point of approximately 168-169°C. It is a chromophoric compound and exhibits a yellow color in solution.

4-(Diethoxymethyl)benzaldehyde can be synthesized through the reaction of benzaldehyde with diethyl carbonate in the presence of a base like potassium carbonate. This method provides good yield and selectivity. Another approach involves the Wittig reaction using ethyl methoxyphosphonate and triphenylphosphine. The chosen method depends on the desired purity and the scale of the synthesis.

4-(Diethoxymethyl)benzaldehyde is primarily used in the pharmaceutical industry for the synthesis of certain drugs. It is also employed in the polymer industry for the modification of polymers to improve their properties. Additionally, it has applications in the production of sensors and semiconductor materials where its chromophoric properties are utilized.

When handling 4-(Diethoxymethyl)benzaldehyde, it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be handled by using suitable absorbents and following the safety data sheet (SDS) guidelines. The compound should be stored in a cool, dry place away from sources of heat and ignition. Proper disposal methods should be followed to ensure environmental safety.