Compound Q&A

How is 4-(Diethoxymethyl)benzaldehyde (CAS: 81172-89-6) typically synthesized?

Answer

4-(Diethoxymethyl)benzaldehyde
4-(Diethoxymethyl)benzaldehyde can be synthesized through the reaction of benzaldehyde with diethyl carbonate in the presence of a base like potassium carbonate. This method provides good yield and selectivity. Another approach involves the Wittig reaction using ethyl methoxyphosphonate and triphenylphosphine. The chosen method depends on the desired purity and the scale of the synthesis.

About

CAS No 81172-89-6
English Name 4-(Diethoxymethyl)benzaldehyde
Molecular Formula C12H16O3
Molecular Weight 208.26 g/mol
SMILES CCOC(OCC)c1ccc(C=O)cc1
InChIKey HTMXMFARWHNJDW-UHFFFAOYSA-N
Last Updated: 2025-09-16 13:49

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