2-Bromo-7-methoxy-9H-carbazole(CAS: 200878-50-8)

2-Bromo-7-methoxy-9H-carbazole is a crystalline solid with a molecular weight of approximately 251.11 g/mol. It has low aqueous solubility but is soluble in organic solvents like chloroform and ethanol. The compound exhibits moderate reactivity towards nucleophiles and electrophiles. It is stable under normal conditions but requires storage in a dry environment to prevent hydrolysis.

2-Bromo-7-methoxy-9H-carbazole is commonly synthesized via the Brønsted acid catalyzed carbazole bromination followed by methoxylation. The reaction typically yields a high purity compound with good selectivity. Commonly used catalysts include hydrogen bromide or phosphorous tribromide, with a yield of around 85-90%.

2-Bromo-7-methoxy-9H-carbazole is utilized in the pharmaceutical industry as a precursor for certain drug synthesis, in the polymer industry for advanced materials, in the semiconductor industry for organic electronic devices, and in the sensor industry for developing gas detection systems. It is also used in organic light-emitting diodes (OLEDs) due to its unique electronic properties.

Proper personal protective equipment (PPE) is essential when handling 2-Bromo-7-methoxy-9H-carbazole. This includes gloves, goggles, and a lab coat. The compound should be handled in a fume hood to minimize exposure. Spills should be cleaned up using a suitable absorbent material, and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for specific handling and disposal instructions.