3-benzyloxy-5-bromo-pyridin-2-amine(CAS: 754230-78-9)

3-benzyloxy-5-bromo-pyridin-2-amine (CAS: 754230-78-9) is a crystalline solid with a molecular weight of approximately 348.14 g/mol. It is slightly soluble in water and more soluble in organic solvents like methanol and ethanol. The compound is relatively stable but can react with strong acids and bases. It exhibits basic properties due to the amine group.

3-benzyloxy-5-bromo-pyridin-2-amine (CAS: 754230-78-9) is typically synthesized through a multi-step process involving the bromination of pyridin-2-amine followed by the introduction of the benzyloxy group. Commonly used reagents include bromine and benzylic halides, with tert-butyldimethylsilyl chloride often used as a coupling agent. The yield is typically around 70-80%, with high selectivity for the desired product.

3-benzyloxy-5-bromo-pyridin-2-amine (CAS: 754230-78-9) is used in the pharmaceutical industry for developing new drug candidates, particularly in the synthesis of biologically active compounds. It also has potential applications in the sensor technology and semiconductor industries, where its chemical properties can be exploited for specific functionalities.

Proper personal protective equipment (PPE) is essential when handling 3-benzyloxy-5-bromo-pyridin-2-amine (CAS: 754230-78-9). Wear gloves, safety goggles, and a lab coat to protect against skin and eye contact. Store the compound in a fume hood to avoid inhalation. In case of a spill, neutralize any acidic or basic reagents and then clean up according to the Material Safety Data Sheet (MSDS) or Safety Data Sheet (SDS). Always handle the compound in a well-ventilated area to avoid exposure to fumes.