α-D-Gulofuranose, 1,2:5,6-bis-O-(1-methylethylidene)-(CAS: 14686-89-6)

α-D-Gulofuranose, 1,2:5,6-bis-O-(1-methylethylidene) (CAS: 14686-89-6) is a cyclic ketose with a molecular weight of approximately 272.3 g/mol. It is a white crystalline solid with a melting point of 179-182 °C. The compound is poorly soluble in water but soluble in ethanol. Chemically, it is highly reactive towards hydrolysis and oxidation.

α-D-Gulofuranose, 1,2:5,6-bis-O-(1-methylethylidene) is typically synthesized by the methylation of gulonic acid using a methyl vinyl ketone as the methylation reagent in the presence of a strong acid catalyst, such as sulfuric acid. The process yields a high purity product with good selectivity and yield.

α-D-Gulofuranose, 1,2:5,6-bis-O-(1-methylethylidene) is primarily used in the pharmaceutical industry for the synthesis of sugar derivatives and in the food industry as a flavoring agent. It also finds applications in the polymer industry for the development of new materials and in the sensors and semiconductors industry for specific chemical sensing applications.

When handling α-D-Gulofuranose, 1,2:5,6-bis-O-(1-methylethylidene) (CAS: 14686-89-6), it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be handled with caution using appropriate absorbents, and the area should be thoroughly cleaned. Always refer to the safety data sheet (SDS) for detailed handling and safety information.