Vonoprazan Fumarate(CAS: 881681-01-2)

Vonoprazan Fumarate is a solid compound with a crystalline form. Its molecular weight is approximately 528.58 g/mol. It has a low solubility in water and good solubility in organic solvents. The compound is stable under normal conditions but can react with strong bases. It is commonly used in pharmaceutical applications.

Vonoprazan Fumarate is synthesized through a multi-step process involving protection, functional group conversion, coupling, and desilylation. The synthesis typically uses mild conditions and a variety of reagents such as N-hydroxysuccinimide and dicyclohexylcarbodiimide. The overall yield is around 70%.

Vonoprazan Fumarate is primarily used in the pharmaceutical industry. It is an active ingredient in medications used to treat gastroesophageal reflux disease (GERD) and peptic ulcers. It is also considered for use in the food industry as a food-grade acid regulator in some preparations.

When handling Vonoprazan Fumarate, appropriate personal protective equipment (PPE) such as gloves and safety goggles should be worn. It should be stored in a cool, dry place away from direct sunlight. In case of a spill, the area should be immediately flushed with water and the material should be cleaned up using appropriate absorbent materials. Always consult the Safety Data Sheet (SDS) for detailed safety information.