(4-Fluorophenyl)(hydroxy)acetic acid(CAS: 395-33-5)

(4-Fluorophenyl)(hydroxy)acetic acid is a white crystalline solid with a molecular weight of approximately 194.13 g/mol. It has a melting point of around 196-198°C and a high solubility in water. This compound is moderately reactive, showing reactivity towards bases and some organic reagents. It is used in various applications requiring its specific reactivity and solubility properties.

(4-Fluorophenyl)(hydroxy)acetic acid can be synthesized by the condensation of 4-fluorophenol with acetic anhydride, followed by hydrolysis. Commonly, this reaction is catalyzed by a strong acid like sulfuric acid, providing good yield and selectivity. The reaction conditions and purity of starting materials are crucial for achieving high-quality products.

(4-Fluorophenyl)(hydroxy)acetic acid finds applications in pharmaceuticals, where its unique structural features can be utilized for drug development. It is also used in the synthesis of certain polymers for their enhanced properties. Additionally, it plays a role in the production of sensors and semiconductors, benefiting from its specific reactivity and solubility characteristics.

Proper handling of (4-Fluorophenyl)(hydroxy)acetic acid requires the use of appropriate personal protective equipment (PPE), such as gloves and safety goggles. It should be stored in a cool, dry place, away from incompatible materials. Handling should be performed in a well-ventilated area or fume hood. In case of spill, avoid inhalation of dust and wash the area thoroughly. Always refer to the Safety Data Sheet (SDS) for detailed safety information.