1-Benzyl-4-piperidinone hydrochloride (1:1)(CAS: 20821-52-7)

1-Benzyl-4-piperidinone hydrochloride (CAS: 20821-52-7) is a white crystalline powder with a molecular weight of approximately 249.8 g/mol. It has a solubility of about 1 g/mL in water. This compound is relatively stable under normal conditions but can be reactive in the presence of strong bases or acids. It has a hydrochloride salt form, which increases its water solubility and enhances its bioavailability.

1-Benzyl-4-piperidinone hydrochloride is typically synthesized via the condensation of benzylamine and 4-piperidone, followed by acidification with hydrochloric acid. Commonly, the reaction is catalyzed by a Lewis acid, such as aluminum chloride, and takes place in an organic solvent like dichloromethane. The yield can reach up to 80% with good selectivity.

1-Benzyl-4-piperidinone hydrochloride (CAS: 20821-52-7) is primarily used in the pharmaceutical industry for its potential as an intermediate in drug synthesis. It also finds applications in the polymer industry, where it can act as a stabilizer or modifier. Additionally, it is used in sensor technology and semiconductor manufacturing due to its chemical reactivity and structural properties.

Proper handling of 1-Benzyl-4-piperidinone hydrochloride (CAS: 20821-52-7) requires the use of personal protective equipment (PPE), including gloves, goggles, and a lab coat. It should be stored in a cool, dry place away from direct sunlight. In case of a spill, it is recommended to use appropriate absorbent materials and ensure proper disposal according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and safety instructions.