2-Methyl-2-propanyl (3S)-3-(hydroxymethyl)-4-morpholinecarboxylate(CAS: 714971-28-5)

2-Methyl-2-propanyl (3S)-3-(hydroxymethyl)-4-morpholinecarboxylate is a solid with a crystalline form. It has a molecular weight of approximately 264.41 g/mol and is slightly soluble in water. It is reactive towards nucleophiles and can undergo esterification and alcoholysis reactions. The compound has a pKa of around 8.6 in aqueous solutions.

2-Methyl-2-propanyl (3S)-3-(hydroxymethyl)-4-morpholinecarboxylate is typically synthesized through a two-step process. First, 4-morpholinecarboxylic acid and 2-methyl-2-propanol are reacted under basic conditions to form the corresponding ester. This ester is then reduced using a hydrogenation catalyst to introduce the hydroxymethyl group.

2-Methyl-2-propanyl (3S)-3-(hydroxymethyl)-4-morpholinecarboxylate is used in the pharmaceutical industry as a precursor for drug synthesis. It also finds applications in sensor technology, particularly in the development of chemical sensors due to its reactivity and functional groups.

When handling 2-Methyl-2-propanyl (3S)-3-(hydroxymethyl)-4-morpholinecarboxylate, it is important to wear appropriate personal protective equipment (PPE) including gloves and safety goggles. The compound should be handled in a fume hood to minimize exposure. In case of spill, it should be immediately contained and cleaned up with appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed safety information.