1H-Purin-2-amine(CAS: 452-06-2)

1H-Purin-2-amine (CAS: 452-06-2) is a solid at room temperature with a melting point of approximately 145°C. Its molecular weight is around 129.14 g/mol. This compound is slightly soluble in water and ethanol. It is known for its basic nature and can react with acids to form purine-2-aminium salts.

1H-Purin-2-amine (CAS: 452-06-2) is often synthesized by the reaction of 2-aminoimidazole with phosphorus oxychloride. This method provides good yield and selectivity. The reaction involves the formation of a purine-2-aminium intermediate, which is then hydrolyzed to yield the target compound.

1H-Purin-2-amine (CAS: 452-06-2) is primarily used in the pharmaceutical industry for the synthesis of purine-based drugs. It also finds applications in the chemical and biochemical research sectors for its basic functional group. Its role in polymer and sensor technology is also explored, though less extensively.

When handling 1H-Purin-2-amine (CAS: 452-06-2), it is essential to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. The compound should be stored in a cool, dry place away from direct sunlight and flammable materials. In case of spill, use a fume hood and follow standard spill cleanup procedures as per the Material Safety Data Sheet (MSDS/SDS).