Compound Q&A

How is 1H-Purin-2-amine (CAS: 452-06-2) typically synthesized?

Answer

1H-Purin-2-amine
1H-Purin-2-amine (CAS: 452-06-2) is often synthesized by the reaction of 2-aminoimidazole with phosphorus oxychloride. This method provides good yield and selectivity. The reaction involves the formation of a purine-2-aminium intermediate, which is then hydrolyzed to yield the target compound.

About

CAS No 452-06-2
English Name 1H-Purin-2-amine
Molecular Formula C5H5N5
Molecular Weight 135.13 g/mol
SMILES C1=C2C(=NC(=N1)N)N=CN2
InChIKey MWBWWFOAEOYUST-UHFFFAOYSA-N
Last Updated: 2025-10-13 11:18

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