Methyl 1H-indole-2-carboxylate(CAS: 1202-04-6)

Methyl 1H-indole-2-carboxylate (CAS: 1202-04-6) is a solid with a crystalline form. It has a molecular weight of approximately 158.19 g/mol and is slightly soluble in water. This compound is reactive, particularly towards nucleophiles. It is used in various organic reactions due to its functional groups.

Methyl 1H-indole-2-carboxylate (CAS: 1202-04-6) can be synthesized via the reaction of indole with acetyl chloride in the presence of a base like triethylamine. The reaction is typically carried out at room temperature, and the yield is about 75-80%. This method provides a good level of selectivity for the carboxylation of the indole ring.

Methyl 1H-indole-2-carboxylate (CAS: 1202-04-6) is used in pharmaceuticals for the synthesis of certain drugs due to its functional groups. It also finds applications in the production of dyes, polymers, and as a precursor in the development of organic electronic devices such as organic semiconductors and sensors.

When handling Methyl 1H-indole-2-carboxylate (CAS: 1202-04-6), it is important to use personal protective equipment (PPE) such as gloves and safety goggles. It should be stored in a well-ventilated area away from ignition sources. In case of a spill, it should be handled with care, and the area should be cleaned with an appropriate solvent. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.