N-[3-(Trifluoromethyl)benzoyl]glycine(CAS: 17794-48-8)

N-[3-(Trifluoromethyl)benzoyl]glycine (CAS: 17794-48-8) is a white crystalline solid with a molecular weight of approximately 334.13 g/mol. It has a high solubility in organic solvents such as dichloromethane and methanol. The compound is moderately reactive, particularly towards nucleophilic substitution reactions. It is stable under normal storage conditions and does not decompose readily under normal laboratory conditions.

N-[3-(Trifluoromethyl)benzoyl]glycine (CAS: 17794-48-8) is typically synthesized via a multi-step process involving the condensation of glycine with 3-(trifluoromethyl)benzoic acid in the presence of a coupling reagent such as HATU and a base like DIPEA. The yield is around 85%, and the product is purified by column chromatography or recrystallization.

N-[3-(Trifluoromethyl)benzoyl]glycine (CAS: 17794-48-8) is primarily used in the pharmaceutical industry for the synthesis of certain bioactive compounds. It also finds applications in the polymer industry as a monomer for the development of specific polymers and in the sensor industry for its unique chemical properties.

When handling N-[3-(Trifluoromethyl)benzoyl]glycine (CAS: 17794-48-8), it is essential to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a laboratory coat. Work should be conducted in a well-ventilated fume hood to minimize exposure. In the event of a spill, avoid direct contact and clean up with appropriate absorbent materials. Refer to the Material Safety Data Sheet (MSDS) for specific handling and disposal instructions.