2'-O-Methylcytidine(CAS: 2140-72-9)

2'-O-Methylcytidine (CAS: 2140-72-9) is a water-soluble compound with a molecular weight of approximately 266.21 g/mol. It forms a white crystalline powder. This compound is relatively stable under normal conditions but can degrade in acidic or strongly basic environments. It is susceptible to hydrolysis and oxidation. It is soluble in polar solvents such as water, ethanol, and DMSO, and slightly soluble in non-polar solvents like hexane and dichloromethane.

2'-O-Methylcytidine (CAS: 2140-72-9) is synthesized through a multi-step process involving alkylation of cytidine with methanol in the presence of a base like sodium hydride. Commonly used catalysts include palladium on carbon, and the reaction is typically carried out under mild conditions. The product is then purified by recrystallization or column chromatography. The yield can range from 50% to 70%, depending on the optimization of the reaction conditions.

2'-O-Methylcytidine (CAS: 2140-72-9) is primarily used in the pharmaceutical industry for the development of antiviral drugs. It is also used in research and development for RNA interference and gene therapy applications. Additionally, it finds applications in the sensor technology industry due to its ability to interact with nucleic acids.

Proper handling of 2'-O-Methylcytidine (CAS: 2140-72-9) requires the use of personal protective equipment (PPE) such as gloves, lab coat, and safety glasses. It should be stored in a cool, dry place away from direct sunlight and heat sources. In case of spills, avoid inhalation and contact with eyes. Spill cleaning should be done using absorbent materials and proper disposal of waste. Always consult the Material Safety Data Sheet (MSDS) for detailed handling instructions and emergency procedures.