(2S)-1-{[5-(3-Methyl-1H-indazol-5-yl)-3-pyridinyl]oxy}-3-phenyl-2-propanamine(CAS: 552325-73-2)

The compound (2S)-1-{[5-(3-Methyl-1H-indazol-5-yl)-3-pyridinyl]oxy}-3-phenyl-2-propanamine has a molecular weight of approximately 431.4 g/mol and is found in a solid crystalline form. It exhibits low water solubility. This compound shows moderate reactivity with bases and is susceptible to hydrolysis under basic conditions. It is not flammable and has a pKa of about 8.5, which indicates its basic nature.

The compound (2S)-1-{[5-(3-Methyl-1H-indazol-5-yl)-3-pyridinyl]oxy}-3-phenyl-2-propanamine can be synthesized via a multistep process involving the reaction of a pyridine derivative with an indazole derivative in the presence of a base such as sodium hydride. The key steps include alkylation and condensation reactions, yielding the target compound with good selectivity and yield. The synthesis typically involves the use of organic solvents like dimethylformamide (DMF) and requires careful handling to achieve the desired product.

The compound (2S)-1-{[5-(3-Methyl-1H-indazol-5-yl)-3-pyridinyl]oxy}-3-phenyl-2-propanamine is primarily used in the pharmaceutical industry for its potential applications as an inhibitor of various enzymes. It may also find use in the polymer industry for its ability to stabilize certain materials, and in the sensor industry for its potential as a chromogenic reagent. Research into its use in semiconductors and electronics is ongoing.

When handling (2S)-1-{[5-(3-Methyl-1H-indazol-5-yl)-3-pyridinyl]oxy}-3-phenyl-2-propanamine (CAS: 552325-73-2), it is important to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal information.