4-Quinolinamine(CAS: 578-68-7)

4-Quinolinamine (CAS: 578-68-7) is a white crystalline solid with a molecular weight of 159.17 g/mol. It has a pKa of 10.1 and is very soluble in water (12.6 g/100 mL at 25°C). It is slightly soluble in ethanol and almost insoluble in benzenes. The compound is moderately reactive and can undergo substitution reactions.

4-Quinolinamine can be synthesized by various methods, including reduction of 4-quinolinecarboxylic acid with hydrogen in the presence of a catalyst like palladium on carbon. Another common method involves the condensation of 4-quinolone with ammonia or an amine compound. The yield and selectivity can vary depending on the chosen method.

4-Quinolinamine (CAS: 578-68-7) is primarily used in the pharmaceutical industry as a precursor for the synthesis of various bioactive compounds. It is also utilized in the production of dyes, sensors, and semiconductor materials. The compound's unique properties make it valuable in these applications.

When handling 4-Quinolinamine (CAS: 578-68-7), it is important to use proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a well-ventilated area and handled in a fume hood to minimize inhalation risks. In case of a spill, immediately clean up the area and consult the safety data sheet (SDS) for further instructions.