3-Hydroxy-N-(2-methoxyphenyl)-2-naphthamide(CAS: 135-62-6)

3-Hydroxy-N-(2-methoxyphenyl)-2-naphthamide (CAS: 135-62-6) is a crystalline solid with a molecular weight of approximately 301.3 g/mol. It is slightly soluble in water and more soluble in organic solvents like ethanol and acetone. This compound exhibits moderate reactivity, particularly in nucleophilic substitution reactions. It has a melting point of around 145-147°C.

3-Hydroxy-N-(2-methoxyphenyl)-2-naphthamide (CAS: 135-62-6) is typically synthesized via a multi-step process starting with naphthaldehyde and methoxybenzaldehyde. The reaction involves condensation followed by an amide formation using an appropriate amine. This method provides high selectivity and good yield, with the final product being purified by recrystallization.

3-Hydroxy-N-(2-methoxyphenyl)-2-naphthamide (CAS: 135-62-6) is used in various industries. It finds applications in pharmaceuticals, where it serves as an intermediate in the synthesis of complex molecules. Additionally, it is utilized in the development of sensors and in the production of specialized polymers and semiconductors.

When handling 3-Hydroxy-N-(2-methoxyphenyl)-2-naphthamide (CAS: 135-62-6), it is essential to wear appropriate personal protective equipment (PPE), including goggles, gloves, and a laboratory coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risk. Spills should be cleaned up using gloves and a suitable absorbent material, and the area should be thoroughly decontaminated. Always refer to the Safety Data Sheet (SDS) for detailed safety information.