(3R)-3-Pyrrolidinol(CAS: 2799-21-5)

(3R)-3-Pyrrolidinol is a colorless liquid with a molecular weight of approximately 101.14 g/mol. It has a pKa of about 10.4. The compound is soluble in water and ethanol. Chemically, it is reactive towards bases and can undergo substitution reactions.

(3R)-3-Pyrrolidinol can be synthesized via the Wittig reaction of 3-bromopyrrolidine with phenyl triphenylphosphonium bromide, yielding a high yield of the desired stereoisomer. Other methods include the reduction of 3-bromopyrrolidone with sodium borohydride.

(3R)-3-Pyrrolidinol is used in the pharmaceutical industry as a precursor for drugs and in polymer chemistry for the synthesis of functionalized polymers. It also finds applications in the production of sensors and as a ligand in catalysis.

When handling (3R)-3-Pyrrolidinol, use appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Store in a cool, dry place away from oxidizing agents. In case of spill, neutralize with an acid and dispose of according to local regulations. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.