4-(Aminomethyl)pyridin-2-amine dihydrochloride(CAS: 618446-34-7)

4-(Aminomethyl)pyridin-2-amine dihydrochloride is a crystalline solid with a molecular weight of approximately 238.74 g/mol. It has a high solubility in water and ethanol. Chemically, it is reactive, particularly with bases and reducing agents. It is a white to off-white crystalline powder, and its dihydrochloride salt form is commonly used in pharmaceuticals and research.

4-(Aminomethyl)pyridin-2-amine dihydrochloride is synthesized by reacting 2-aminopyridine with methylamine hydrochloride in the presence of a suitable base such as sodium hydroxide. The reaction mixture is then treated with hydrochloric acid to form the dihydrochloride salt. The yield is typically high, and the reaction is carried out under mild conditions.

4-(Aminomethyl)pyridin-2-amine dihydrochloride is primarily used in the pharmaceutical industry as an intermediate for drug synthesis. It also finds applications in sensor technology and electronic materials, particularly in the development of organic semiconductors and polymer-based materials.

When handling 4-(Aminomethyl)pyridin-2-amine dihydrochloride, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risk. Spills should be cleaned up immediately using appropriate absorbents, and the material should be stored in a secure, sealed container to prevent contamination. Always refer to the safety data sheet (SDS) for detailed handling and storage instructions.