6-Methyl-16-methylene-3,20-dioxopregna-4,6-dien-17-yl acetate(CAS: 2919-66-6)

6-Methyl-16-methylene-3,20-dioxopregna-4,6-dien-17-yl acetate (CAS: 2919-66-6) is a crystalline solid with a molecular formula C22H30O4 and a molecular weight of approximately 358.48 g/mol. It has low solubility in water but is soluble in organic solvents like ethanol and acetone. This compound is relatively stable under normal conditions but reacts with strong bases and acids. It has a melting point around 70-72°C.

6-Methyl-16-methylene-3,20-dioxopregna-4,6-dien-17-yl acetate is synthesized through a series of reactions starting from progesterone. The process involves acetylation of a specific intermediate, followed by ring opening and methylation steps. Common catalysts include acid catalysts and transition metal complexes, with high selectivity and a yield of up to 85%.

6-Methyl-16-methylene-3,20-dioxopregna-4,6-dien-17-yl acetate (CAS: 2919-66-6) is primarily used in the pharmaceutical industry for the synthesis of progestins and other steroid hormones. It is also explored in research for its potential in polymers and sensors due to its unique chemical structure.

When handling 6-Methyl-16-methylene-3,20-dioxopregna-4,6-dien-17-yl acetate (CAS: 2919-66-6), use appropriate personal protective equipment (PPE) such as gloves and a lab coat. Store it in a cool, dry place, away from direct sunlight and heat sources. Work in a well-ventilated area or a fume hood. In case of spills, use absorbent material and follow local safety guidelines. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal information.