Benzyl 4-nitrophenyl carbonate(CAS: 13795-24-9)

Benzyl 4-nitrophenyl carbonate (CAS: 13795-24-9) is a white crystalline solid with a molecular weight of approximately 284.14 g/mol. It has moderate solubility in organic solvents but is poorly soluble in water. This compound is known for its reactivity in organic synthesis, particularly in coupling reactions and as a coupling reagent in the formation of carbon-nitrogen bonds.

Benzyl 4-nitrophenyl carbonate (CAS: 13795-24-9) is typically synthesized via the reaction of benzoic acid and 4-nitrophenol with phosgene. The process is catalyzed by a base such as triethylamine or pyridine, and the reaction is carried out in an inert solvent like methylene chloride. The yield and selectivity of the reaction are highly dependent on the choice of catalyst and reaction conditions.

Benzyl 4-nitrophenyl carbonate (CAS: 13795-24-9) is primarily used in the pharmaceutical industry for the synthesis of various organic compounds, including intermediates for drug synthesis. It also finds applications in the polymer industry as a coupling agent, and in the development of sensors and semiconductors where its reactivity properties are utilized.

When handling Benzyl 4-nitrophenyl carbonate (CAS: 13795-24-9), it is essential to use personal protective equipment (PPE) such as gloves, safety goggles, and lab coats. This compound should be stored in a cool, dry place, away from sources of heat and ignition. In case of a spill, it is important to use appropriate spill response materials and to consult the Safety Data Sheet (SDS) for detailed instructions.