2-Methyl-2-propanyl {(4R,6S)-6-[(E)-2-{4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl}vinyl]-2,2-dimethyl-1,3-dioxan-4-yl}acetate(CAS: 289042-12-2)

This compound has a crystalline form at room temperature. The molecular weight is approximately 624.8 g/mol. It has limited water solubility and is more soluble in organic solvents. Reactivity is moderate, with potential for ring-opening reactions under certain conditions. It is not highly reactive but should be handled with care due to its chemical complexity.

Synthesis typically involves multi-step processes, including the formation of an acetal followed by a ring-opening reaction with a pyrimidine derivative. Specific catalysts such as Lewis acids can be used to improve selectivity. The overall yield is moderate, around 50-70%, and the reaction is carried out under anhydrous conditions to prevent unwanted side reactions.

This compound is primarily used in the pharmaceutical industry for the development of novel anti-cancer and anti-inflammatory drugs. It may also have applications in the polymer industry for developing advanced materials and in the sensor industry for the detection of specific analytes.

Handle this compound under a fume hood due to its potential for volatility and reactivity. Wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Spills should be cleaned up immediately according to the Material Safety Data Sheet (MSDS/SDS). It is important to consult the SDS for detailed safety information and follow all laboratory safety protocols.