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Cathelicidin(CAS: 154947-66-7)
CAS Number
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Basic Information
Molecular Formula
C205H340N60O53
Molecular Weight
4493 g/mol
Chemical Identifiers
SMILES
CCC(C)C(C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CCC(=O)O)C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CCCCN)C(=O)NC(CCCNC(=N)N)C(=O)NC(C(C)CC)C(=O)NC(C(C)C)C(=O)NC(CCC(=O)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(C(C)CC)C(=O)NC(CCCCN)C(=O)NC(CC(=O)O)C(=O)NC(CC2=CC=CC=C2)C(=O)NC(CC(C)C)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(=O)N)C(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(=O)N3CCCC3C(=O)NC(CCCNC(=N)N)C(=O)NC(C(C)O)C(=O)NC(CCC(=O)O)C(=O)NC(CO)C(=O)O)NC(=O)C(CCCCN)NC(=O)C(CCC(=O)O)NC(=O)C(CCCCN)NC(=O)C(CO)NC(=O)C(CCCCN)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC4=CC=CC=C4)NC(=O)C(CC5=CC=CC=C5)NC(=O)C(CC(=O)O)NC(=O)CNC(=O)C(CC(C)C)NC(=O)C(CC(C)C)N
InChIKey
POIUWJQBRNEFGX-XAMSXPGMSA-N
Database References
MDL Number
MFCD09264694
FAQ
Cathelicidin (CAS: 154947-66-7) is a small antimicrobial peptide with a molecular weight of approximately 1.5 kDa. It is highly soluble in water and has good stability. Cathelicidin is reactive towards bacterial cell membranes due to its cationic nature and amphipathic structure. It exists in a crystalline form suitable for storage and transport.
Cathelicidin (CAS: 154947-66-7) can be synthesized through solid-phase peptide synthesis using Fmoc chemistry. Commonly, the peptide is synthesized on a resin, with Fmoc protecting groups removed stepwise. The sequence is then deprotected and the peptide is cleaved from the solid support using trifluoroacetic acid (TFA). This method provides good selectivity and yields are typically around 70-80%.
Cathelicidin (CAS: 154947-66-7) has applications primarily in the pharmaceutical industry, where it is used for developing antimicrobial therapies. It is also utilized in research for studying host defense peptides and has potential uses in sensor technology for detecting pathogens.
When handling Cathelicidin (CAS: 154947-66-7), it is essential to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. Handle in a fume hood to avoid inhalation. Spills should be managed carefully using absorbent materials and disposed of according to local regulations. Always refer to the safety data sheet (SDS) for detailed handling instructions.
Safety Notice
Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.
Always follow proper handling procedures
Contact Information
Contact Person
Tang Silei
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