(2R,3R)-rel-1-(Dimethylamino)-3-(3-methoxyphenyl)-2-methylpentan-3-ol(CAS: 175590-76-8)

(2R,3R)-rel-1-(Dimethylamino)-3-(3-methoxyphenyl)-2-methylpentan-3-ol is a colorless liquid with a molecular weight of approximately 245.34 g/mol. It has a pKa of around 9.4 due to the dimethylamino group, indicating basic properties. The compound is moderately soluble in water but highly soluble in organic solvents such as ethanol and acetone. Chemically, it is relatively stable but can react with strong acids or bases. It is not reactive towards common electrophiles or nucleophiles at room temperature.

(2R,3R)-rel-1-(Dimethylamino)-3-(3-methoxyphenyl)-2-methylpentan-3-ol is typically synthesized via a multistep process involving the formation of an intermediate ketone followed by reduction and alkylation reactions. The synthesis involves the use of a palladium catalyst and a base such as sodium tert-butoxide. High selectivity and yield are achieved through careful control of reaction conditions, such as temperature, solvent, and catalyst loading.

(2R,3R)-rel-1-(Dimethylamino)-3-(3-methoxyphenyl)-2-methylpentan-3-ol is used in the pharmaceutical industry as an intermediate in the synthesis of certain drugs. It also finds applications in the production of sensors and semiconductors due to its unique chemical properties. Additionally, it is utilized in the polymer industry for the development of novel materials with specific functionalities.

When handling (2R,3R)-rel-1-(Dimethylamino)-3-(3-methoxyphenyl)-2-methylpentan-3-ol, appropriate personal protective equipment (PPE) should be worn, including gloves, goggles, and a lab coat. The substance should be handled in a well-ventilated area or within a fume hood to minimize exposure. Spills should be cleaned up immediately using appropriate absorbent materials and the area should be thoroughly rinsed with water. Always refer to the Safety Data Sheet (SDS) for specific handling and disposal instructions. This compound is not particularly hazardous, but care should be taken to avoid inhalation or skin contact.