5-Chloro-4-quinolinamine(CAS: 92385-37-0)

5-Chloro-4-quinolinamine is a white to yellowish crystalline solid with a molecular weight of approximately 199.57 g/mol. Its solubility in water is 0.4 g/L. It is moderately reactive and can be used in pharmaceutical applications. This compound is known for its biological activity and can exhibit alkaline properties.

5-Chloro-4-quinolinamine is usually synthesized through the reaction of 4-aminobenzoic acid and chlorine gas in the presence of a dehydrating agent, such as phosphorus oxychloride. The yield of the reaction can be up to 85%, and the selectivity is good. This method provides a straightforward route to the compound.

5-Chloro-4-quinolinamine is primarily used in the pharmaceutical industry due to its biological activity. It can also be used in the production of certain polymers and as a precursor in the development of sensors and semiconductors.

When handling 5-Chloro-4-quinolinamine, it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be handled in a well-ventilated area or a fume hood. Spills should be cleaned up immediately with appropriate absorbent materials. Safety data sheets (SDS) should be consulted for detailed safety information and emergency procedures.