4-Bromo-1-isoindolinone(CAS: 337536-15-9)

4-Bromo-1-isoindolinone (CAS: 337536-15-9) is a white crystalline solid with a molecular weight of approximately 248.03 g/mol. It is slightly soluble in water but soluble in common organic solvents like ethanol and acetone. This compound exhibits good thermal stability but is susceptible to bromine displacement reactions, making it reactive in certain chemical environments.

4-Bromo-1-isoindolinone can be synthesized through the bromination of 1-isoindolinone using bromine in the presence of an appropriate base like sodium hydroxide. The reaction is typically carried out in an inert solvent such as tetrahydrofuran (THF) at room temperature. This method provides good yield and selectivity for this brominated derivative.

4-Bromo-1-isoindolinone (CAS: 337536-15-9) is primarily used in the pharmaceutical industry for the synthesis of various drug candidates. It also finds applications in the polymer industry as a precursor for functional polymers. Additionally, it is utilized in the sensor and semiconductor industries due to its specific chemical reactivity and functional groups.

When handling 4-Bromo-1-isoindolinone (CAS: 337536-15-9), it is essential to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. This compound should be stored in a cool, dry place, away from heat and direct sunlight. In case of a spill, immediately contain the spill using absorbent materials and consult the Safety Data Sheet (SDS) for further instructions. Always work in a well-ventilated area or a fume hood to minimize inhalation risks.