2-Chloroethyl 4-methylbenzenesulfonate(CAS: 80-41-1)

2-Chloroethyl 4-methylbenzenesulfonate (CAS: 80-41-1) is a crystalline solid with a molecular weight of approximately 242.64 g/mol. It has a low solubility in water (0.15 g/100 mL at 20°C) and is more soluble in organic solvents like dimethylformamide. This compound is reactive, particularly towards nucleophiles and reducing agents, and can undergo substitution reactions.

2-Chloroethyl 4-methylbenzenesulfonate is typically synthesized through the reaction of 4-methylbenzenesulfonic acid with ethyl chloride in the presence of a base like sodium hydroxide. The process involves nucleophilic substitution and typically yields a product with high purity. The reaction is carried out under mild conditions to ensure selectivity and a good yield.

2-Chloroethyl 4-methylbenzenesulfonate (CAS: 80-41-1) is used in various industries, including pharmaceuticals for synthesis of intermediates, polymers for functional additives, and electronics for semiconductor manufacturing. It also finds applications in sensors as a reagent and in the production of certain chemical intermediates.

When handling 2-Chloroethyl 4-methylbenzenesulfonate (CAS: 80-41-1), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to avoid inhalation of fumes. Spills should be handled with caution, and appropriate safety data sheets (SDS) should be consulted for detailed spill procedures. Ensure proper storage in a cool, dry place, away from incompatible materials.