5-chloro-6-hydroxynicotinic acid(CAS: 54127-63-8)

5-Chloro-6-hydroxynicotinic acid (CAS: 54127-63-8) is a solid with a white crystalline form. It has a molecular weight of approximately 174.58 g/mol and is slightly soluble in water. It is moderately reactive and can undergo substitution reactions. The compound is stable under normal conditions but should be stored in a sealed container to prevent moisture absorption.

5-Chloro-6-hydroxynicotinic acid (CAS: 54127-63-8) can be synthesized via a multi-step process. Common methods include the chlorination of 6-hydroxynicotinic acid followed by acidification. This process requires careful control of temperature and pH to achieve high yield and selectivity. Catalysts such as sulfuric acid are often used in the chlorination step.

5-Chloro-6-hydroxynicotinic acid (CAS: 54127-63-8) is primarily used in the pharmaceutical and chemical industries. It is a key intermediate in the synthesis of various drugs and can be used as a building block for further chemical modifications in the development of new pharmaceuticals. Additionally, it has applications in the production of certain dyes and pigments.

When handling 5-chloro-6-hydroxynicotinic acid (CAS: 54127-63-8), it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. It should be stored in a well-ventilated area and used in a fume hood to minimize exposure. Spills should be cleaned up using appropriate absorbent materials and the area flushed with water. Refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.