Compound Q&A

How is 5-chloro-6-hydroxynicotinic acid (CAS: 54127-63-8) typically synthesized?

Answer

5-chloro-6-hydroxynicotinic acid
5-Chloro-6-hydroxynicotinic acid (CAS: 54127-63-8) can be synthesized via a multi-step process. Common methods include the chlorination of 6-hydroxynicotinic acid followed by acidification. This process requires careful control of temperature and pH to achieve high yield and selectivity. Catalysts such as sulfuric acid are often used in the chlorination step.

About

CAS No 54127-63-8
English Name 5-chloro-6-hydroxynicotinic acid
Molecular Formula C6H4ClNO3
Molecular Weight 173.56 g/mol
SMILES C1=C(C(=O)NC=C1C(=O)O)Cl
InChIKey OLTRUTPHSBQWAZ-UHFFFAOYSA-N
Last Updated: 2025-10-10 12:21

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