Methyl 4-iodo-1-methyl-1H-pyrazole-5-carboxylate(CAS: 75092-26-1)

Methyl 4-iodo-1-methyl-1H-pyrazole-5-carboxylate (CAS: 75092-26-1) is a crystalline solid with a molecular weight of approximately 336.03 g/mol. It has a low solubility in water but is more soluble in organic solvents like methanol and dichloromethane. The compound is moderately reactive, particularly towards nucleophilic substitution reactions. It exhibits good thermal stability but can decompose under strongly acidic conditions.

Methyl 4-iodo-1-methyl-1H-pyrazole-5-carboxylate (CAS: 75092-26-1) is typically synthesized via the iodination of methyl 1-methyl-1H-pyrazole-5-carboxylate with N-iodosuccinimide (NIS) in the presence of potassium iodide as a catalyst. The reaction yields a high selectivity for the desired product with good to moderate yields depending on the reaction conditions.

Methyl 4-iodo-1-methyl-1H-pyrazole-5-carboxylate (CAS: 75092-26-1) is primarily used in the pharmaceutical industry for the synthesis of various medicinal compounds. It also has potential applications in polymer chemistry and semiconductor manufacturing, where its unique chemical properties can be exploited.

Handling Methyl 4-iodo-1-methyl-1H-pyrazole-5-carboxylate (CAS: 75092-26-1) requires appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be stored in a cool, dry place away from direct sunlight and incompatible materials. Spills should be cleaned up using appropriate absorbent materials, and the area should be well-ventilated. Always consult the Safety Data Sheet (SDS) for detailed safety information.