Compound Q&A

How is Methyl 4-iodo-1-methyl-1H-pyrazole-5-carboxylate (CAS: 75092-26-1) typically synthesized?

Answer

Methyl 4-iodo-1-methyl-1H-pyrazole-5-carboxylate
Methyl 4-iodo-1-methyl-1H-pyrazole-5-carboxylate (CAS: 75092-26-1) is typically synthesized via the iodination of methyl 1-methyl-1H-pyrazole-5-carboxylate with N-iodosuccinimide (NIS) in the presence of potassium iodide as a catalyst. The reaction yields a high selectivity for the desired product with good to moderate yields depending on the reaction conditions.

About

CAS No 75092-26-1
English Name Methyl 4-iodo-1-methyl-1H-pyrazole-5-carboxylate
Molecular Formula C6H7IN2O2
Molecular Weight 266.04 g/mol
SMILES CN1C(=C(C=N1)I)C(=O)OC
InChIKey OTYGSOJERQNQFY-UHFFFAOYSA-N
Last Updated: 2025-10-28 10:54

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