Ophiobolin A(CAS: 4611-05-6)

Ophiobolin A (CAS: 4611-05-6) is a cyclic depsipeptide with a molecular weight of approximately 449.37 g/mol. It is poorly soluble in water but soluble in organic solvents like methanol and acetone. Ophiobolin A is relatively stable under normal conditions but shows increased reactivity towards acidic conditions. It crystallizes in the form of colorless needles at room temperature.

Ophiobolin A (CAS: 4611-05-6) is typically synthesized through solid-phase peptide synthesis (SPPS) followed by deprotection and coupling steps. Commonly used catalysts include t-Boc and Fmoc protecting groups. The synthetic route involves multiple steps of amino acid coupling, deprotection, and purification, yielding a product with high selectivity and yield.

Ophiobolin A (CAS: 4611-05-6) is primarily used in the pharmaceutical industry due to its antifungal and antibiotic properties. It is also of interest in the agricultural sector for developing fungicides. Additionally, it has potential applications in the sensor technology and material science industries for its unique chemical and physical properties.

When handling Ophiobolin A (CAS: 4611-05-6), it is important to wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be immediately cleaned up using appropriate absorbent materials, and the area should be thoroughly washed down. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.