3-{[(Tert-butoxy)carbonyl]amino}bicyclo[1.1.1]pentane-1-carboxylic acid(CAS: 303752-38-7)

3-{[(Tert-butoxy)carbonyl]amino}bicyclo[1.1.1]pentane-1-carboxylic acid is a white crystalline solid with a molecular weight of approximately 264.37 g/mol. It has a melting point around 179°C and is slightly soluble in water. The compound is known for its reactivity in esterification and amide formation reactions. It is used in organic synthesis as an intermediate.

3-{[(Tert-butoxy)carbonyl]amino}bicyclo[1.1.1]pentane-1-carboxylic acid is synthesized through a multi-step reaction involving the use of tert-butoxycarbonyl chloride, aminobicyclo[1.1.1]pentane, and a suitable base like triethylamine. The process involves the formation of an amide bond and the protection of the amino group with a tert-butoxycarbonyl group.

3-{[(Tert-butoxy)carbonyl]amino}bicyclo[1.1.1]pentane-1-carboxylic acid is primarily used in the pharmaceutical and chemical industries. It serves as a key intermediate in the synthesis of various drugs and other organic compounds. Additionally, it may be used in the polymer industry for the production of functional polymers with specific properties.

When handling 3-{[(Tert-butoxy)carbonyl]amino}bicyclo[1.1.1]pentane-1-carboxylic acid, it is important to use appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Handle the compound in a well-ventilated area or a fume hood to avoid inhalation of dust or vapors. Spills should be cleaned up using appropriate absorbent materials and flushed with water. Always consult the material safety data sheet (MSDS/SDS) for detailed safety information.