1-Oxoisoindoline-4-carbonitrile(CAS: 435273-34-0)

1-Oxoisoindoline-4-carbonitrile is a crystalline solid with a molecular weight of approximately 198.14 g/mol. It is poorly soluble in water but soluble in organic solvents such as dichloromethane and acetonitrile. The compound shows moderate reactivity towards nucleophiles and is susceptible to hydrolysis under basic conditions.

1-Oxoisoindoline-4-carbonitrile is typically synthesized via the reaction of isoindolinone with hydrogen cyanide in the presence of a base. The process requires careful control of reaction conditions to achieve high yield and selectivity. Commonly used bases include potassium hydroxide or sodium hydroxide.

1-Oxoisoindoline-4-carbonitrile is used in the pharmaceutical industry for the synthesis of certain drug molecules. It also finds applications in the polymer industry as a monomer for specific polymerization processes. Other industries that may use this compound include the electronics industry for semiconductor manufacturing and the sensor industry for developing chemical sensors.

When handling 1-Oxoisoindoline-4-carbonitrile, it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be performed in a fume hood to minimize exposure. Spills should be handled carefully using appropriate absorbents and reported to a supervisor. Always refer to the Safety Data Sheet (SDS) for specific handling instructions and emergency procedures.