20-Methoxy-20-oxoicosanoic acid(CAS: 1767-98-2)

20-Methoxy-20-oxoicosanoic acid is a solid at room temperature, forming a white crystalline powder. Its molecular weight is approximately 364.46 g/mol. The compound is slightly soluble in water and has good solubility in organic solvents like ethanol and acetone. It is chemically stable, but it can react with strong bases to form sodium salts or similar derivatives.

20-Methoxy-20-oxoicosanoic acid can be synthesized via the Wittig reaction using 20-methoxy-20-hydroxyicosanone and phosphorus ylide. This reaction provides good yield and selectivity. The process involves the use of a coupling agent and a base, typically performed under anhydrous conditions to avoid hydrolysis.

20-Methoxy-20-oxoicosanoic acid is primarily used in the pharmaceutical industry for various applications, including as a precursor in the synthesis of drugs and prodrugs. It also finds applications in the polymer industry as an additive to enhance properties such as flexibility and resistance. Additionally, it is used in the development of certain sensor materials and as a component in some semiconductors.

When handling 20-Methoxy-20-oxoicosanoic acid, it is advisable to wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to avoid inhalation. Spills should be cleaned up carefully, using appropriate absorbent materials, and the area should be thoroughly rinsed. Always refer to the Safety Data Sheet (SDS) for specific handling and disposal instructions.