(4S)-4-Benzyl-3-propionyl-1,3-oxazolidin-2-one(CAS: 101711-78-8)

(4S)-4-Benzyl-3-propionyl-1,3-oxazolidin-2-one is a crystalline compound with a molecular weight of approximately 254.34 g/mol. It has a solubility of about 60 mg/mL in water and is practically insoluble in most organic solvents. It exhibits good stability under normal conditions but is reactive towards nucleophiles and bases, making it useful in organic synthesis and pharmaceutical applications.

(4S)-4-Benzyl-3-propionyl-1,3-oxazolidin-2-one can be synthesized via the condensation of propionyl chloride with 4-benzyl-1,3-oxazolidin-2-one, using a catalytic amount of triethylamine. The reaction is typically carried out under mild conditions, and the yield is usually around 80-90%. This compound is also prepared via the hydrolysis of 4-benzyl-3-propionoyl-1,3-oxazolidin-2-one, which provides a higher yield and better purity.

(4S)-4-Benzyl-3-propionyl-1,3-oxazolidin-2-one is widely used in the pharmaceutical industry as a precursor for the synthesis of various drug candidates. It is also utilized in the preparation of polymers, sensors, and materials science applications. Its versatility makes it a valuable compound in organic synthesis and research.

When handling (4S)-4-Benzyl-3-propionyl-1,3-oxazolidin-2-one, it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a laboratory coat. The compound should be handled in a well-ventilated area or a fume hood. Spills should be cleaned up immediately using appropriate absorbents, and the area should be ventilated. Always consult the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.