4-(3-Pyridinyloxy)aniline(CAS: 80650-45-9)

4-(3-Pyridinyloxy)aniline is a white to off-white solid with a molecular weight of approximately 224.21 g/mol. It has a high solubility in organic solvents like DMF and poor solubility in water. Chemically, it is stable under normal conditions but can react with strong oxidizing agents. It is a 2-aminopyridinium derivative used in various applications.

4-(3-Pyridinyloxy)aniline is typically synthesized via the reaction of pyridine-3-carboxaldehyde with aniline in the presence of an acid catalyst, such as sulfuric acid. The yield is usually around 80%, and the reaction involves the substitution of the hydroxyl group on the pyridine ring with an amino group.

4-(3-Pyridinyloxy)aniline is used in the pharmaceutical industry for the synthesis of certain drugs, in polymer chemistry for the development of functional polymers, and in the manufacturing of sensors and semiconductors for their electronic properties.

Proper personal protective equipment (PPE) such as gloves, goggles, and lab coats should be worn when handling 4-(3-Pyridinyloxy)aniline. It should be stored in a cool, dry place away from direct sunlight. In case of a spill, use appropriate containment measures and refer to the Safety Data Sheet (SDS) for disposal instructions and emergency procedures.