2-Bromo-1-(phenylsulphonyl)-1H-indole(CAS: 121963-39-1)

2-Bromo-1-(phenylsulphonyl)-1H-indole is a solid compound with a molecular weight of approximately 311.23 g/mol. It is poorly soluble in water but soluble in organic solvents like ethanol and acetone. Chemically, it is highly reactive towards nucleophiles and can undergo substitution reactions.

2-Bromo-1-(phenylsulphonyl)-1H-indole is typically synthesized by bromination of 1-(phenylsulphonyl)-1H-indole using N-bromosuccinimide (NBS) in the presence of an organic solvent like acetonitrile. The reaction is conducted under light or heat to achieve a high yield of the target compound.

2-Bromo-1-(phenylsulphonyl)-1H-indole is primarily used in the pharmaceutical industry for the synthesis of various drugs. It also has applications in the polymer industry for functionalizing polymers and in the sensor industry for developing chemical sensors.

When handling 2-Bromo-1-(phenylsulphonyl)-1H-indole, it is essential to wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a lab coat. Work in a fume hood to minimize exposure to bromine fumes. In case of a spill, use appropriate absorbent materials and follow the safety data sheet (SDS) for disposal instructions.