1-Bromo-3-ethynylbenzene(CAS: 766-81-4)

1-Bromo-3-ethynylbenzene (CAS: 766-81-4) is a crystalline solid with a molecular weight of approximately 171.03 g/mol. It is slightly soluble in water but soluble in organic solvents like ethanol and acetone. Chemically, it is highly reactive with nucleophiles and can undergo electrophilic aromatic substitution and addition reactions. Its density is around 1.12 g/cm³.

1-Bromo-3-ethynylbenzene (CAS: 766-81-4) is typically synthesized by reacting ethynylbenzene with bromine in the presence of a Lewis acid catalyst such as iron(III) bromide. The reaction is performed under anhydrous conditions to achieve good selectivity and yield. The product can be isolated by crystallization from a suitable solvent.

1-Bromo-3-ethynylbenzene (CAS: 766-81-4) is used in various industries. It serves as a precursor in the synthesis of pharmaceuticals, polymers, and organic semiconductors. Additionally, it is employed in the development of sensors and as an intermediate in chemical processes.

When handling 1-Bromo-3-ethynylbenzene (CAS: 766-81-4), it is essential to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or a fume hood to prevent inhalation. Spills should be immediately cleaned up with appropriate chemicals, and the area should be well-ventilated. Always consult the Safety Data Sheet (SDS) for detailed safety information and procedures.