Compound Q&A

How is 1-Bromo-3-ethynylbenzene (CAS: 766-81-4) typically synthesized?

Answer

1-Bromo-3-ethynylbenzene
1-Bromo-3-ethynylbenzene (CAS: 766-81-4) is typically synthesized by reacting ethynylbenzene with bromine in the presence of a Lewis acid catalyst such as iron(III) bromide. The reaction is performed under anhydrous conditions to achieve good selectivity and yield. The product can be isolated by crystallization from a suitable solvent.

About

CAS No 766-81-4
English Name 1-Bromo-3-ethynylbenzene
Molecular Formula C8H5Br
Molecular Weight 181.03 g/mol
SMILES C#CC1=CC(=CC=C1)Br
InChIKey TZDXNFAAJNEYIO-UHFFFAOYSA-N
Last Updated: 2025-10-10 19:08

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