Ethyl 2-amino-1,3-oxazole-4-carboxylate(CAS: 177760-52-0)

Ethyl 2-amino-1,3-oxazole-4-carboxylate (CAS: 177760-52-0) is a white crystalline solid with a molecular weight of approximately 194.25 g/mol. It is slightly soluble in water and more soluble in organic solvents like dichloromethane and ethanol. This compound exhibits good reactivity towards nucleophiles and can undergo various chemical transformations. It has a pKa of around 4.5, indicating moderate acidity.

Ethyl 2-amino-1,3-oxazole-4-carboxylate (CAS: 177760-52-0) is typically synthesized via the condensation of ethyl 2-amino-1,3-oxazole-4-carboxylate with appropriate reagents. Common synthetic routes involve the use of sodium hydride and ethyl 2-amino-1,3-oxazole-4-carboxylate. The reaction is usually carried out in anhydrous organic solvents, and the yield can be up to 90% under optimized conditions.

Ethyl 2-amino-1,3-oxazole-4-carboxylate (CAS: 177760-52-0) has applications in the pharmaceutical industry, where it serves as a precursor for the synthesis of various bioactive compounds. It is also utilized in the polymer industry for the development of novel materials with improved properties. Additionally, it finds use in sensor technology and semiconductor manufacturing due to its unique chemical properties and reactivity.

When handling Ethyl 2-amino-1,3-oxazole-4-carboxylate (CAS: 177760-52-0), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up immediately using appropriate absorbents, and the area should be thoroughly rinsed. Safety data sheets (SDS) should be consulted for detailed handling and disposal instructions.