N-{3-[(5-Bromo-4-{[2-(1H-imidazol-4-yl)ethyl]amino}-2-pyrimidinyl)amino]phenyl}-1-pyrrolidinecarboxamide(CAS: 702674-56-4)

N-{3-[(5-Bromo-4-{[2-(1H-imidazol-4-yl)ethyl]amino}-2-pyrimidinyl)amino]phenyl}-1-pyrrolidinecarboxamide has a crystalline form with a molecular weight of approximately 514.24 g/mol. It is sparingly soluble in water and ethanol. The compound is reactive towards nucleophiles and can undergo substitution reactions. Its solubility and reactivity make it suitable for various chemical processes.

N-{3-[(5-Bromo-4-{[2-(1H-imidazol-4-yl)ethyl]amino}-2-pyrimidinyl)amino]phenyl}-1-pyrrolidinecarboxamide is synthesized via a multi-step reaction involving alkylation and amidation. The synthesis involves the use of 5-bromopyrimidine and 1H-imidazole, with catalysts such as potassium carbonate. The yield is around 70%, and the process is selective and efficient.

N-{3-[(5-Bromo-4-{[2-(1H-imidazol-4-yl)ethyl]amino}-2-pyrimidinyl)amino]phenyl}-1-pyrrolidinecarboxamide is primarily used in the pharmaceutical industry for drug development due to its unique chemical structure. It also finds applications in the polymer industry for specialized polymer synthesis and in the semiconductor industry as a functional material.

When handling N-{3-[(5-Bromo-4-{[2-(1H-imidazol-4-yl)ethyl]amino}-2-pyrimidinyl)amino]phenyl}-1-pyrrolidinecarboxamide, lab technicians should wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The compound should be handled in a fume hood to prevent inhalation. In case of a spill, it is recommended to clean it up using appropriate spill response materials and follow safety data sheet (SDS) guidelines for disposal. The compound is potentially reactive and should be stored in a cool, dry place away from sources of heat and ignition.