Compound Q&A
How is N-{3-[(5-Bromo-4-{[2-(1H-imidazol-4-yl)ethyl]amino}-2-pyrimidinyl)amino]phenyl}-1-pyrrolidinecarboxamide (CAS: 702674-56-4) typically synthesized?
Answer
![N-{3-[(5-Bromo-4-{[2-(1H-imidazol-4-yl)ethyl]amino}-2-pyrimidinyl)amino]phenyl}-1-pyrrolidinecarboxamide](https://static.chemtradehub.com/structs/702/702674-56-4-97e3.webp "N-{3-[(5-Bromo-4-{[2-(1H-imidazol-4-yl)ethyl]amino}-2-pyrimidinyl)amino]phenyl}-1-pyrrolidinecarboxamide")
N-{3-[(5-Bromo-4-{[2-(1H-imidazol-4-yl)ethyl]amino}-2-pyrimidinyl)amino]phenyl}-1-pyrrolidinecarboxamide is synthesized via a multi-step reaction involving alkylation and amidation. The synthesis involves the use of 5-bromopyrimidine and 1H-imidazole, with catalysts such as potassium carbonate. The yield is around 70%, and the process is selective and efficient.
About
CAS No
702674-56-4
English Name
N-{3-[(5-Bromo-4-{[2-(1H-imidazol-4-yl)ethyl]amino}-2-pyrimidinyl)amino]phenyl}-1-pyrrolidinecarboxamide
Molecular Formula
C20H23BrN8O
Molecular Weight
471.36 g/mol
SMILES
C1CCN(C1)C(=O)NC2=CC=CC(=C2)NC3=NC=C(C(=N3)NCCC4=CN=CN4)Br
InChIKey
DMMILYKXNCVKOJ-UHFFFAOYSA-N
Last Updated: 2025-10-17 07:35
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