tert-butyl N-[(2R)-2-hydroxypropyl]carbamate(CAS: 119768-44-4)

Tert-butyl N-[(2R)-2-hydroxypropyl]carbamate (CAS: 119768-44-4) is a colorless to slightly yellow oily liquid at room temperature. Its molecular weight is approximately 202.24 g/mol. It is slightly soluble in water and miscible with organic solvents. It is reactive towards nucleophiles and can undergo hydrolysis under basic conditions.

Tert-butyl N-[(2R)-2-hydroxypropyl]carbamate (CAS: 119768-44-4) is typically synthesized by the reaction of tert-butyl isocyanate with 2-hydroxypropylamine. The reaction is catalyzed by a basic compound such as triethylamine and proceeds with good yield and selectivity.

Tert-butyl N-[(2R)-2-hydroxypropyl]carbamate (CAS: 119768-44-4) is used in the pharmaceutical industry for the synthesis of certain active pharmaceutical ingredients. It is also utilized in the polymer industry for improving the properties of polymers and in the manufacturing of sensors and semiconductors.

When handling tert-butyl N-[(2R)-2-hydroxypropyl]carbamate (CAS: 119768-44-4), appropriate personal protective equipment (PPE) should be worn, including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or under a fume hood. Spills should be cleaned up immediately and safely according to the Material Safety Data Sheet (MSDS/SDS).