2,6-dimethoxypyrimidin-4-amine(CAS: 3289-50-7)

2,6-Dimethoxypyrimidin-4-amine (CAS: 3289-50-7) has a crystalline form with a molecular weight of approximately 198.17 g/mol. It is sparingly soluble in water but soluble in common organic solvents like ethanol and dichloromethane. The compound is moderately reactive and can undergo nucleophilic substitution reactions. It is stable under normal laboratory conditions but should be stored away from direct sunlight and heat sources.

2,6-Dimethoxypyrimidin-4-amine (CAS: 3289-50-7) is typically synthesized via a multistep process involving the reaction of 2,6-dimethoxypyridine with hydrazine hydrate. The synthesis involves mild heating and typically uses hydrazine hydrate as the primary reagent. The yield is generally good, around 70-80%, and the reaction is known to be selective under these conditions.

2,6-Dimethoxypyrimidin-4-amine (CAS: 3289-50-7) is primarily used in the pharmaceutical industry as a precursor for the synthesis of various pyrimidine-based drugs. It also has applications in the polymer industry for the development of advanced materials and as a functional group in organic synthesis for the preparation of other heterocyclic compounds.

When handling 2,6-dimethoxypyrimidin-4-amine (CAS: 3289-50-7), it is important to wear appropriate Personal Protective Equipment (PPE) including gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated fume hood to minimize exposure. Spills should be cleaned up using appropriate absorbent materials and the area should be flushed with water. It is advisable to refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.