(1s,5s)-1,5-Dimethyl-3,7-diazabicyclo[3.3.1]nonan-9-one(CAS: 80808-96-4)

(1s,5s)-1,5-Dimethyl-3,7-diazabicyclo[3.3.1]nonan-9-one has a melting point of 77-79°C, a molecular weight of 190.23 g/mol, and is slightly soluble in water. It is an amphoteric compound, exhibiting both acidic and basic properties. It is reactive towards nucleophiles and electrophiles due to its conjugated structure.

(1s,5s)-1,5-Dimethyl-3,7-diazabicyclo[3.3.1]nonan-9-one can be synthesized via the Corey-Kim modification of the Wittig olefination. The synthesis involves the reaction of (Z)-5,9-dimethyl-1,5-diphenyl-3,7-diaza-bicyclo[3.3.1]non-3-en-9-one with methyl iodide in the presence of a base like sodium hydride, yielding a high yield of the desired product.

(1s,5s)-1,5-Dimethyl-3,7-diazabicyclo[3.3.1]nonan-9-one is primarily used in the pharmaceutical and polymer industries. It serves as a precursor in the synthesis of various bioactive compounds and is also utilized in the development of novel materials and sensors.

When handling (1s,5s)-1,5-Dimethyl-3,7-diazabicyclo[3.3.1]nonan-9-one, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up using appropriate absorbents, and the area should be ventilated thoroughly. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.