Amoxapine(CAS: 14028-44-5)

Amoxapine is an antipsychotic and antidepressant drug with a molecular formula of C17H21NO. It has a molecular weight of approximately 259.36 g/mol. Amoxapine is sparingly soluble in water and has a crystalline form. It is not highly reactive but may undergo hydrolysis under acidic conditions. It is stable under normal storage conditions.

Amoxapine is synthesized via a multi-step process involving the protection of a hydroxyl group, followed by amidation and deprotection. Commonly used catalysts in the amidation step include coupling reagents like HATU. The overall synthesis yields approximately 70-80%, with good selectivity and purity.

Amoxapine is primarily used in the pharmaceutical industry due to its psychiatric applications. It is not commonly used in other industries like polymers, sensors, or semiconductors. However, it may be used in pharmaceutical research and development.

When handling Amoxapine, wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Store in a cool, dry place away from direct sunlight. Avoid contact with eyes and skin, and ensure good ventilation. In case of spill, use appropriate spill kits and follow safety data sheet (SDS) guidelines for disposal.